anti- BCL10 antibody

Host

Rabbit

Uniprot ID

O95999

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Involved in adaptive immune response(PubMed:25365219). Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1(PubMed:18264101).

Immunogen

B-cell CLL/lymphoma 10

Synonyms

BCL10, Cellular homolog of vCARMEN, CLAP, CARMEN, CARD like apoptotic protein

Observed MW

32kd

Reactivity

Human, Mouse

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:500-1:1000; IHC: 1:20-1:200

Gene ID

8915

Research Area

Immunology, Signal Transduction