anti- BAX antibody

Host

Mouse

Uniprot ID

Q07812

Form

liquid

Purification

Protein A+G purification

Purity

? 95% as determined by SDS-PAGE

Clonality

monoclonal

Clone ID

5F4

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

Immunogen

BCL2-associated X protein

Synonyms

BCL2L4

Observed MW

21 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB,IHC,IF

Recommended dilution

WB: 1:1000-1:10000; IHC: 1:400-1:1000; IF: 1:50-1:500

Gene ID

581

Research Area

Neuroscience, Cancer, Developmental biology