anti- BANP antibody

Host

Rabbit

Uniprot ID

Q8N9N5

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Controls V(D)J recombination during T-cell development by repressing T-cell receptor(TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta(S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest(By similarity).

Immunogen

BTG3 associated nuclear protein

Synonyms

BANP, BEND1, Protein BANP, SMAR1, SMARBP1

Observed MW

56kd

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, IHC, WB

Recommended dilution

WB: 1:500-1:1000; IHC: 1:50-1:500

Gene ID

54971

Research Area

Metabolism, Developmental biology