anti- BAG1S-specific antibody

Host

Rabbit

Uniprot ID

Q99933

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

BAG1 have been identified that modulate gene transcription through poorly defined mechanisms. Four isoforms of the BAG1 protein (BAG1S, BAG1, BAG1M and BAG1L) can be produced from a common mRNA by use of alternative translation initiation sites, including a non-canonical CTG codon in one instance. The longest, BAG1L (Mr ~50K), contains a nuclear localization signal (NLS) and resides in the nucleus, whereas BAG1M (Mr ~46K) has an incomplete NLS and distributes mainly in cytosol, unless dragged into the nucleus through interactions with other. Distribution of BAG1S(p33) is not clear yet. This antibody recongizes all the isoforms of BAG1, includes GAG1L, BAG1V, BAG1M and BAG1S.

Immunogen

BCL2-associated athanogene

Synonyms

Observed MW

45 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:500-1:1000; IHC: 1:20-1:200

Gene ID

573

Research Area

Cardiovascular, Signal Transduction