anti- ATP11B antibody

Host

Rabbit

Uniprot ID

Q9Y2G3

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules(Probable). Involved in regulation of sensitivity to cisplatin; may contribute to secretory vesicle transport of cisplatin from Golgi to plasma membrane.

Immunogen

ATPase, class VI, type 11B

Synonyms

ATP11B, ATPase class VI type 11B, ATPase IR, ATPase, class VI, type 11B, ATPIF, ATPIR, KIAA0956

Observed MW

12 kDd

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, IHC

Recommended dilution

IHC: 1:20 - 1:200

Gene ID

23200

Research Area

Metabolism