anti- ASTL antibody

Host

Rabbit

Uniprot ID

Q6HA08

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding(By similarity).

Immunogen

astacin-like metallo-endopeptidase(M12 family)

Synonyms

ASTL, Oocyte astacin, Ovastacin, SAS1B

Observed MW

46 kDa

Reactivity

Human

Tested Application

ELISA, WB

Recommended dilution

WB: 1:500-1:1000

Gene ID

431705

Research Area

Stem Cells, Metabolism