anti- ARRDC3 antibody

Host

Rabbit

Uniprot ID

Q96B67

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors(PubMed:20559325, PubMed:21982743, PubMed:23208550). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation(PubMed:20559325, PubMed:23208550). May recruit NEDD4 to ADRB2(PubMed:20559325). Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes(PubMed:23208550).

Immunogen

arrestin domain containing 3

Synonyms

ARRDC3, arrestin domain containing 3, KIAA1376, TLIMP

Observed MW

46 kDa

Reactivity

Human

Tested Application

ELISA, WB, IF

Recommended dilution

WB: 1:500-1:1000; IF: 1:10-1:100

Gene ID

57561

Research Area

Metabolism