anti- ARL13B antibody

Host

Rabbit

Uniprot ID

Q3SXY8

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. May regulate endocytic recycling traffic; however, additional evidences are required to confirm these data.

Immunogen

ADP-ribosylation factor-like 13B

Synonyms

ARL13B, ARL2 like protein 1, ARL2L1, JBTS8

Observed MW

40-48 kDa, 66 kDa

Reactivity

Human, Mouse, Rat, Dog

Tested Application

ELISA, WB, IHC, IP, IF

Recommended dilution

WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:200

Gene ID

200894

Research Area

Signal Transduction