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Dima Biotech

SKU:DMC101378

Anti-AREG antibody(1B12), IgG1 Chimeric mAb

Anti-AREG antibody(1B12), IgG1 Chimeric mAb

Regular price $446.00 USD
Regular price Sale price $446.00 USD
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Clone ID

1B12

Target

Synonyms

AR;CRDGF;AREGB;SDGF

Host Species

Rabbit

Description

Anti-AREG antibody(1B12), IgG1 Chimeric mAb

Delivery

In Stock

Uniprot ID

P15514

IgG type

Rabbit/Human Fc chimeric IgG1

Clonality

Monoclonal

Reactivity

Human

Applications

Flow Cyt

Purification

Purified from cell culture supernatant by affinity chromatography

Formulation & Reconstitution

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage & Shipping

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Background

The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]

Usage

Research use only

Conjugate

Unconjugated

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