anti- ARAP3 antibody

Host

Rabbit

Uniprot ID

Q8WWN8

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate(PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate(PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin.

Immunogen

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

Synonyms

CENTD3

Observed MW

45 kDa

Reactivity

Human

Tested Application

ELISA, IHC

Recommended dilution

IHC: 1:20-1:200

Gene ID

64411

Research Area

Signal Transduction