anti- APPL1 antibody

Host

Rabbit

Uniprot ID

Q9UKG1

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway.

Immunogen

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

Synonyms

APPL, DIP13A,

Observed MW

80kd

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IF, IHC, IP

Recommended dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID

26060

Research Area

Neuroscience, Signal Transduction