anti- APAF1 antibody

Host

Rabbit

Uniprot ID

O14727

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9(Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

Immunogen

apoptotic peptidase activating factor 1

Synonyms

APAF 1, APAF1, CED4, KIAA0413

Observed MW

140 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IP, IF

Recommended dilution

WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200

Gene ID

317

Research Area

Developmental biology