anti- AP4M1 antibody

Host

Rabbit

Uniprot ID

O00189

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Component of the AP-4 complex, a novel type of clathrin-or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network(TGN) to the endosomal-lysosomal system. Plays a role in the intracellular trafficking of APP from the trans-Golgi network(TGN) to endosomes, and thereby inhibits amyloidogenic processing of APP.

Immunogen

adaptor-related protein complex 4, mu 1 subunit

Synonyms

MUARP2

Observed MW

50-55 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, IHC, WB

Recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Gene ID

9179

Research Area

Signal Transduction, Metabolism