anti- ANO2 antibody

Host

Rabbit

Uniprot ID

Q9NQ90

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Calcium-activated chloride channel(CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors(OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.

Immunogen

anoctamin 2

Synonyms

ANO2, anoctamin 2, C12orf3, DKFZp434P102, TMEM16B, Transmembrane protein 16B

Observed MW

114 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IF, IP, IHC

Recommended dilution

WB: 1:1000-1:10000; IHC: 1:20-1:200; IF: 1:10-1:100; IP: 1:200-1:1000

Gene ID

57101

Research Area

Neuroscience