anti- Angiogenin antibody

Host

Rabbit

Uniprot ID

P03950

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Angiogenin(ANG), a angiogenic ribonuclease, is a member of the vertebrate-specific, secreted RNASE superfamily. Angiogenin, originally identified as a tumor angiogenic factor, was related with the growth and metastasis of numerous tumors. Angiogenin is also a component of normal human plasma and follicular Xuid. Its widespread expression in human tissues suggests angiogenin may have biological functions in addition to the promotion of angiogenesis. Recently, its biological activity has been extended to stimulating cell proliferation and promoting cell survival. It is a 17 kDa precursor which is cleaved to generate the 14 kDa mature protein.

Immunogen

angiogenin, ribonuclease, RNase A family, 5

Synonyms

ALS9, ANG, Angiogenin, HEL168, Ribonuclease 5, RNase 5, RNASE4, RNASE5

Observed MW

17 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:200-1:2000; IHC: 1:50-1:500

Gene ID

Research Area

Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology, Neuroscience