anti- Amylin antibody

Host

Rabbit

Uniprot ID

P10997

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

IAPP, also known as Amylin, is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. IAPP is co-secreted with insulin by pancreatic β-cells and largely contributes to glycemic control. Studies suggest that this protein, like the related beta-amyloid(Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

Immunogen

islet amyloid polypeptide

Synonyms

Amylin, DAP, Diabetes associated peptide, IAP, IAPP, Insulinoma amyloid peptide, islet amyloid polypeptide

Observed MW

10 kDa

Reactivity

Human

Tested Application

ELISA, IHC

Recommended dilution

IHC: 1:20-1:200

Gene ID

3375

Research Area

Signal Transduction