anti- AMPK alpha 2 antibody

Host

Rabbit

Uniprot ID

P54646

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

PRKAA2(protein kinase, AMP-activated, alpha 2 catalytic subunit), also named as AMPKA2, AMPK, PRKAA, AMPK2, belonogs to the CAMK Ser/Thr protein kinase family and SNF1 subfamily. PRKAA2 is an αβγ heterotrimer that is activated by low cellular energy status, such as decreases in both the ATP/AMP ratio and the phosphocreatine content and it is a glycogen synthase kinase, phosphorylating Ser7 at the NH2 terminus, which decreases glycogen synthase activity(PMID:14532170). The protein can be ubiquitinated(PMID:21224036).

Immunogen

protein kinase, AMP-activated, alpha 2 catalytic subunit

Synonyms

AMPK, AMPK alpha 2, AMPK subunit alpha 2, AMPK2, PRKAA, PRKAA2

Observed MW

62 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IF, IHC, IP

Recommended dilution

WB: 1:1000-1:10000; IHC: 1:20-1:200; IF: 1:10-1:100; IP:1:500-1:5000

Gene ID

Research Area

Cardiovascular, Metabolism, Signal Transduction