anti- AMOT antibody

Host

Mouse

Uniprot ID

Q4VCS5

Form

liquid

Purification

Protein A+G purification

Purity

? 95% as determined by SDS-PAGE

Clonality

monoclonal

Clone ID

2C9

Isotype

IgG2b

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.

Immunogen

angiomotin

Synonyms

AMOT, angiomotin, KIAA1071

Observed MW

130 kDa

Reactivity

Human

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:1000-1:10000; IHC: 1:20-1:200

Gene ID

154796

Research Area

Cardiovascular, Developmental biology