anti- ALX1 antibody

Host

Rabbit

Uniprot ID

Q15699

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes(PubMed:9753625, PubMed:8756334). Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival(PubMed:20451171). May also induce epithelial to mesenchymal transition(EMT) through the expression of SNAI1(PubMed:23288509).

Immunogen

ALX homeobox 1

Synonyms

ALX homeobox 1, ALX homeobox protein 1, ALX1, CART 1, CART1, Cartilage homeoprotein 1

Observed MW

37 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, WB

Recommended dilution

WB: 1:200-1:2000

Gene ID

8092

Research Area

Metabolism, Developmental biology