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ABCbiolab

SKU:ABCF00340

anti- ALR antibody

anti- ALR antibody

Regular price $240.00 USD
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size
Host
Uniprot ID

Host

Rabbit

Uniprot ID

P55789

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

as determined by SDS-PAGE

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background

The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene.

Immunogen

growth factor, augmenter of liver regeneration

Synonyms

ALR, ERV1, GFER, Hepatopoietin, HERV1, HPO, HPO1, HPO2, HSS

Observed MW

23 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Gene ID

2671

Research Area

Stem Cells, Metabolism, Developmental biology

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