SKU:ABCF00309
anti- alpha 1 Antichymotrypsin / AACT antibody
anti- alpha 1 Antichymotrypsin / AACT antibody
Host
Rabbit
Uniprot ID
P01011
Form
liquid
Purification
Immunogen affinity purified
Purity
>= 95%
as determined by SDS-PAGEClonality
polyclonal
Clone ID
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
Immunogen
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
Synonyms
A1 Antichymotrypsin, AACT, ACT, Alpha 1 antichymotrypsin, GIG24, GIG25, Serpin A3, SERPINA3
Observed MW
50 kDa
Reactivity
Human, Mouse, Rat
Tested Application
ELISA, IHC, WB, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200
Gene ID
12
Research Area
Cancer, Immunology, Cardiovascular, Metabolism