anti- ALKBH4 antibody

Host

Rabbit

Uniprot ID

Q9NXW9

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84'(K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation.

Immunogen

alkB, alkylation repair homolog 4(E. coli)

Synonyms

ALKBH4, FLJ20013, ABH4

Observed MW

34 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IF

Recommended dilution

WB: 1:200-1:2000; IHC: 1:10-1:100

Gene ID

54784

Research Area

Metabolism