anti- Aldolase C antibody

Host

Mouse

Uniprot ID

P09972

Form

liquid

Purification

Protein A+G purification

Purity

? 95% as determined by SDS-PAGE

Clonality

monoclonal

Clone ID

6F3

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Fructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).

Immunogen

aldolase C, fructose-bisphosphate

Synonyms

ALDOC, Aldolase C, Brain type aldolase, Fructose bisphosphate aldolase C

Observed MW

39 kDa

Reactivity

Human

Tested Application

ELISA, WB, IHC, IF

Recommended dilution

WB: 1:5000-1:50000; IHC: 1:50-1:500; IF: 1:20-1:200

Gene ID

230

Research Area

Metabolism