anti- ALDH1A2 antibody

Host

Rabbit

Uniprot ID

O94788

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background

This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

Immunogen

aldehyde dehydrogenase 1 family, member A2

Synonyms

ALDH1A2, RALDH 2, RALDH(II), RALDH2, RALDH2 T, Retinal dehydrogenase 2

Observed MW

57 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Gene ID

8854

Research Area

Metabolism