anti- AKT antibody

Host

Mouse

Uniprot ID

P31749

Form

liquid

Purification

Protein A+G purification

Purity

? 95% as determined by SDS-PAGE

Clonality

monoclonal

Clone ID

8H0

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. This antibody detects all the members of AKT with/without phospho-modification.

Immunogen

v-akt murine thymoma viral oncogene homolog 1

Synonyms

AKT, AKT1, AKT2, AKT3, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha

Observed MW

56-62 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IF, IP

Recommended dilution

WB: 1:1000-1:10000; IP: 1:500-1:5000; IHC: 1:100-1:400; IF: 1:10-1:100

Gene ID

207

Research Area

Metabolism, Cardiovascular, Immunology, Developmental biology, Neuroscience, Stem Cells