anti- AKNA antibody

Host

Rabbit

Uniprot ID

Q7Z591

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

AKNA also named as AT hook transcription factor is a 1439 amino-acids protein. AKNA, encodes a lymphoid-specific AT-hook transcription factor that is highly expressed by B and T lymphocytes. It coordinately regulates expression of the CD40 receptor and its ligand (CD154), two molecules that are critical for antigen-dependent B-cell development. AKNA expresses at least nine distinct transcripts, some of which are expressed in a tissue-specific manner. These transcripts are products of alternative splicing, alternative promoter usage, and alternative polyadenylation. The alternative AKNA transcripts are predicted to encode overlapping protein isoforms, some of which (p70 and p100) (PMID:15869410)

Immunogen

AT-hook transcription factor

Synonyms

AKNA, AT hook transcription factor, FLJ31001, FLJ33184, KIAA1968, RP11 82I1.4

Observed MW

155 kDa, observed 65-70 kDa

Reactivity

Human

Tested Application

ELISA, IHC, WB

Recommended dilution

WB: 1:200-1:2000; IF: 1:20-200

Gene ID

80709

Research Area

Metabolism