anti- AFAP1 antibody

Host

Rabbit

Uniprot ID

Q8N556

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Can cross-link actin filaments into both network and bundle structures(By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.

Immunogen

actin filament associated protein 1

Synonyms

AFAP, AFAP 110, AFAP1, FLJ56849

Observed MW

81 kDa, 110 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IF

Recommended dilution

WB: 1:500-1:5000; IF: 1:10-1:100

Gene ID

60312

Research Area

Signal Transduction