anti- AF-6 antibody

Host

Rabbit

Uniprot ID

P55196

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

MLLT4, also named as AF6 and Afadin, belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions(AJs). It is a nNectin-and actin-filament-binding protein that connects nectin to the actin cytoskeleton. The antibody is specific to MLLT4.

Immunogen

myeloid/lymphoid or mixed-lineage leukemia(trithorax homolog, Drosophila); translocated to, 4

Synonyms

AF 6, AF6, AFADIN, Afadin variant, MLLT4

Observed MW

207 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB

Recommended dilution

WB: 1:500-1:2000

Gene ID

4301

Research Area

Signal Transduction