anti- ADHFE1 antibody

Host

Rabbit

Uniprot ID

Q8IWW8

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate(GHB) to succinic semialdehyde(SSA) coupled to reduction of 2-ketoglutarate(2-KG) to D-2-hydroxyglutarate(D-2-HG). D,L-3-hydroxyisobutyrate and L-3-hydroxybutyrate(L-3-OHB) are also substrates for HOT with 10-fold lower activities.

Immunogen

alcohol dehydrogenase, iron containing, 1

Synonyms

ADH8, ADHFE1, FLJ32430, HMFT2263, HOT

Observed MW

50 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IP

Recommended dilution

WB: 1:1000-1:10000; IHC: 1:20-1:200; IP: 1:200-1:1000

Gene ID

137872

Research Area

Metabolism