anti- ACVRL1 antibody

Host

Rabbit

Uniprot ID

P37023

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.

Immunogen

activin A receptor type II-like 1

Synonyms

Activin receptor like kinase 1, ACVRL1, ACVRLK1, ALK 1, ALK1, HHT, HHT2, ORW2, SKR3, TSR I

Observed MW

56 kDa

Reactivity

Human

Tested Application

ELISA, WB, IHC, FC, IP

Recommended dilution

WB: 1:200-1:1000; IHC: 1:100-1:400; IP: 1:200-1:1000

Gene ID

94

Research Area

Cardiovascular, Metabolism, Signal Transduction