anti- ACVR1C antibody

Host

Rabbit

Uniprot ID

Q8NER5

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).

Immunogen

activin A receptor, type IC

Synonyms

ACVR1C, Activin receptor type 1C, Activin receptor type IC, ACVRLK7, ALK 7

Observed MW

60 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

Gene ID

130399

Research Area

Stem Cells, Signal Transduction, Metabolism