anti- 5 Lipoxygenase antibody

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95% as determined by SDS-PAGE

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

ALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene(cys-LT) production, critical mediators in asthma(PMID:12911785).

Immunogen

arachidonate 5-lipoxygenase

Synonyms

5 Lipoxygenase, 5 LO, 5 LOX, 5LPG, ALOX5, LOG5

Observed MW

75 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, IF, WB

Recommended dilution

WB: 1:200-1:2000; IF: 1:20-1:100

Gene ID

Research Area

Metabolism

Host

Rabbit

Uniprot ID

P09917