anti- 15 Lipoxygenase 2 antibody

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95% as determined by SDS-PAGE

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

In humans, there are 6 functional lipoxygenases genes. Two of them encode for arachidonic acid 12-lipoxygenating(ALOX12, ALOX12B) and two for 15-lipoxygenating enzymes(ALOX15, ALOX15B). ALOX15B has been described as the most abundant 15-lipoxygenating enzyme species in human carotid atherosclerotic lesions and to be associated with cerebrovascular symptoms.(PMID:24373925). ALOX15B has 4 isoforms produced by alternative splicing with the MW of 76, 67, 69 and 73 kDa.

Immunogen

arachidonate 15-lipoxygenase, type B

Synonyms

ALOX15B;Arachidonate 15-lipoxygenase B,15-LOX-B,15-LOX-2,Arachidonate 15-lipoxygenase type II,Linoleate 13-lipoxygenase 15-Lob

Observed MW

76 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC,IF

Recommended dilution

WB: 1:200-1:2000; IHC: 1:20-1:200

Gene ID

Research Area

Metabolism

Host

Rabbit

Uniprot ID

O15296