ANG I Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from the N-terminal region of human ANG. AA range:11-60

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

16550

synonyms

Angiogenin; ANG; RNASE5; Angiogenin; Ribonuclease 5; RNase 5