AMPD3 Polyclonal Antibody

Ab type

Primary antibody

Background

AMPD3 encodes a member of the AMP deaminase gene family. The adenosine monophosphate deaminase 3 is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from AMPD3 . at AA range: 280-360

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

88812

synonyms

AMPD3; AMP deaminase 3; AMP deaminase isoform E; Erythrocyte AMP deaminase