ALX1 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

ALX homeobox 1 antibody; ALX homeobox protein 1 antibody; ALX1 antibody; ALX1_HUMAN antibody; CART 1 antibody; CART-1 antibody; CART1 antibody; Cartilage homeoprotein 1 antibody; Cartilage paired class homeoprotein 1 antibody; FND3 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q15699

Immunogen

Recombinant Human ALX homeobox protein 1 protein (10-304AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes (PubMed:9753625, PubMed:8756334). Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival (PubMed:20451171). May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1 (PubMed:23288509).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ALX1

Research Areas

Epigenetics and Nuclear Signaling; Developmental biology; Stem cells