ALS Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by IGFALS is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human IGFALS. AA range:303-352

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

66035

synonyms

IGFALS; ALS; Insulin-like growth factor-binding protein complex acid labile subunit; ALS