alpha-Skeletal Muscle Actin Polyclonal Antibody

Ab type

Primary antibody

Background

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthetic Peptide of α-Skeletal Muscle Actin

Storage Stability

-20°C for 1 year

Concentration

MolecularWeight_Da

42051

synonyms

Actin alpha skeletal muscle; ACTA1; ACTA; Actin, alpha skeletal muscle; Alpha-actin-1