ALKBH3 Antibody

Size

100ul

Clone Number

Aliases

1700108H04Rik antibody; 1810020C19Rik antibody; ABH3 antibody; AlkB homolog 3 antibody; alkB; alkylation repair homolog 3 (E. coli) antibody; ALKB3_HUMAN antibody; ALKBH3 antibody; Alkylated DNA repair protein alkB homolog 3 antibody; alkylation repair homolog 3 antibody; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 antibody; DEPC 1 antibody; DEPC-1 antibody; DEPC1 antibody; EC 1.14.11. antibody; FLJ43614 antibody; mABH3 antibody; MGC118790 antibody; MGC118792 antibody; MGC118793 antibody; MGC134125 antibody; PCA1 antibody; Prostate cancer antigen 1 antibody; Prostate cancer antigen-1 antibody; RP23-375N21.4 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q96Q83

Immunogen

Recombinant Human Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 protein (1-286AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ALKBH3

Research Areas

Epigenetics and Nuclear Signaling