Aldose Reductase Polyclonal Antibody

Ab type

Primary antibody

Background

AKR1B1 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member (aldo-keto reductase family 1 member B) catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.

Reactivity

Human;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human AKR1B1. AA range:241-290

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

35853

synonyms

AKR1B1; ALDR1; Aldose reductase; AR; Aldehyde reductase; Aldo-keto reductase family 1 member B1