ALDH1A2 Polyclonal Antibody

Ab type

Primary antibody

Background

This protein ALDH1A2 belongs to the aldehyde dehydrogenase family of proteins. The product of ALDH1A2 (aldehyde dehydrogenase 1 family member A2) is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for ALDH1A2.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human ALDH1A2. AA range:412-461

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

56724

synonyms

ALDH1A2; RALDH2; Retinal dehydrogenase 2; RALDH 2; RalDH2; Aldehyde dehydrogenase family 1 member A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II)