AKR7A2 Antibody

Size

100ul

Clone Number

Aliases

AFAR antibody; AFAR1 antibody; AFB1 aldehyde reductase 1 antibody; AFB1 AR1 antibody; AFB1-AR 1 antibody; AFB1AR1 antibody; Aflatoxin aldehyde reductase antibody; Aflatoxin B1 aldehyde reductase member 2 antibody; Aflatoxin beta1 aldehyde reductase antibody; Aiar antibody; AKR7 antibody; Akr7a2 antibody; Aldo keto reductase family 7 antibody; Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase antibody; Aldo keto reductase family 7 member A2 antibody; Aldo keto reductase family 7; member A2 (aflatoxin aldehyde reductase) antibody; Aldoketoreductase 7 antibody; ARK72_HUMAN antibody; SSA reductase antibody; Succinic semialdehyde reductase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O43488

Immunogen

Recombinant Human Aflatoxin B1 aldehyde reductase member 2 protein (100-359AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

AKR7A2

Research Areas

Neuroscience; Cancer; Metabolism; Signal transduction