AKR1C3 Antibody

Size

100ul

Clone Number

Aliases

17 beta HSD 5 antibody; 17 beta hydroxysteroid dehydrogenase type 5 antibody; 17-beta-HSD 5 antibody; 17-beta-hydroxysteroid dehydrogenase type 5 antibody; 2-dihydrobenzene-1 antibody; 2-diol dehydrogenase antibody; 20 alpha-hydroxysteroid dehydrogenase antibody; 20-alpha-hydroxysteroid dehydrogenase antibody; 3 alpha hydroxysteroid dehydrogenase type II antibody; 3-alpha-HSD type 2 antibody; 3-alpha-HSD type II antibody; 3-alpha-HSD type II; brain antibody; 3-alpha-hydroxysteroid dehydrogenase type 2 antibody; AK1C3_HUMAN antibody; AKR1 C3 antibody; Akr1c18 antibody; AKR1C3 antibody; Aldo keto reductase family 1 member C3 antibody; Aldo-keto reductase family 1 member C3 antibody; brain antibody; Chlordecone reductase antibody; Chlordecone reductase homolog HAKRb antibody; DD-3 antibody; DD3 antibody; DDH1 antibody; DDX antibody; Dihydrodiol dehydrogenase 3 antibody; Dihydrodiol dehydrogenase type I antibody; Dihydrodiol dehydrogenase X antibody; HA1753 antibody; HAKRB antibody; HAKRe antibody; hluPGFS antibody; HSD17B5 antibody; Indanol dehydrogenase antibody; KIAA0119 antibody; PGFS antibody; Prostaglandin F synthase antibody; Testosterone 17-beta-dehydrogenase 5 antibody; Trans-1 antibody; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase antibody; Type IIb 3 alpha hydroxysteroid dehydrogenase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P42330

Immunogen

Recombinant Human Aldo-keto reductase family 1 member C3 protein (1-323AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IP; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IP:1:200-1:2000

Background

Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

AKR1C3

Research Areas

Neuroscience; Cancer; Metabolism; Signal transduction