AK1C4 Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human protein . at AA range: 1-80

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Aldo-keto reductase family 1 member C4 ;EC 1.1.1.-;3-alpha-HSD1;3-alpha-hydroxysteroid dehydrogenase type I;EC 1.1.1.50;Chlordecone reductase;CDR;EC 1.1.1.225;Dihydrodiol dehydrogenase 4