AGRIN Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ)| as identified in mouse knock-out studies. The encoded protein contains several laminin G| Kazal type serine protease inhibitor| and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles| a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human protein . at AA range: 1900-1980

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Agrin