AGO1 Antibody

Size

100ul

Clone Number

Aliases

AGO1 antibody; AGO1_HUMAN antibody; Argonaute 1 antibody; Argonaute 1 RISC catalytic component antibody; Argonaute1 antibody; eIF 2C 1 antibody; eIF-2C 1 antibody; eIF2C 1 antibody; EIF2C antibody; Eif2c1 antibody; Eukaryotic translation initiation factor 2C 1 antibody; GERP95 antibody; Golgi Endoplasmic Reticulum protein 95 kDa antibody; hAgo1 antibody; Protein argonaute 1 antibody; Protein argonaute-1 antibody; Putative RNA binding protein Q99 antibody; Putative RNA-binding protein Q99 antibody; Q99 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UL18

Immunogen

Recombinant Human Protein argonaute-1 protein (251-400AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Background

Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

AGO1

Research Areas

Signal Transduction