AGK Antibody

Size

100ug

Clone Number

Aliases

2610037M15Rik antibody; 6720408I04Rik antibody; Acylglycerol Kinase antibody; Acylglycerol kinase mitochondrial antibody; Acylglycerol kinase; mitochondrial antibody; agk antibody; AGK_HUMAN antibody; AI465370 antibody; FLJ10842 antibody; hAGK antibody; HsMuLK antibody; MuLK antibody; Multi substrate lipid kinase antibody; Multi-substrate lipid kinase antibody; Multiple substrate lipid kinase antibody; RGD1562046 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q53H12

Immunogen

Recombinant Human Acylglycerol kinase, mitochondrial protein (32-65AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

AGK

Research Areas

Cancer; Metabolism; Signal transduction