ADRBK1 Monoclonal Antibody

Size

Clone Number

Aliases

GRK2, BARK1, BETA-ARK1

Immunogen Species

Human

UniProt ID

P25098

Immunogen

Purified recombinant human ADRBK1(C-term.) protein fragments expressed in E.coli.

Raised in

Mouse

Species Reactivity

Human,Rat,Mouse,Pig,Dog

Tested Applications

ELISA,WB;Recommended dilution:WB:1:500-1:5000

Background

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1.

Clonality

Monoclonal

Isotype

IgG1

Purification Method

Affinity purified

Conjugate

Non-conjugated

Buffer

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ADRBK1

Research Areas

Neuroscience;Signal transduction