ADGRE2 Antibody

Size

100ug

Clone Number

Aliases

CD 312 antibody; CD 312 antigen antibody; CD312 antibody; CD312 antigen antibody; Egf like module containing mucin like hormone receptor like 2 antibody; Egf like module containing mucin like hormone receptor like sequence 2 antibody; EGF like module EMR2 antibody; EGF-like module receptor 2 antibody; EGF-like module-containing mucin-like hormone receptor-like 2 antibody; EMR2 antibody; EMR2_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UHX3

Immunogen

Recombinant Human Adhesion G protein-coupled receptor E2 protein (151-323AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200

Background

Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation (PubMed:26841242).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ADGRE2

Research Areas

Signal transduction