ADA15 Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain| a disintegrin-like domain| as well as a EGF-like domain. Through its disintegrin-like domain| this protein specifically interacts with the integrin beta chain| beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner| suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human protein . at AA range: 50-130

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Disintegrin and metalloproteinase domain-containing protein 15 ;ADAM 15;EC 3.4.24.-;Metalloprotease RGD disintegrin protein;Metalloproteinase-like; disintegrin-like; and cysteine-rich protein 15